Partial remission in new onset T1D New Definition for the Partial Remission Period in Children and Adolescents with T1D
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چکیده
1 Glostrup University Hospital, Department of Paediatrics, Glostrup, Denmark, 2 Department of Statistics, University of Southern Denmark, Denmark 3 Leicester Royal Infirmary Children’s Hospital, Leicester, United Kingdom 4 University of Ulm, Germany, 5 Trinity College , National Childrens Hospital, Dublin, Ireland 6 Ulleval University Hospital, Department of Pediatrics, Oslo, Norway 7 Clinique Pediatrique, Centre Hospitalier de Luxembourg 8 Clinica Pediatrica Universita, Chieti, Italy, 9 Kinderkrankenhaus auf der Bult, Department of Paediatrics, Hannover, Germany 10 University Children’s Hospital, Zurich, Switzerland, 11 Regionsjukhuset i Örebro, Örebro, Sweden
منابع مشابه
A predictive model for lack of partial clinical remission in new-onset pediatric type 1 diabetes
IMPORTANCE >50% of patients with new-onset type 1 diabetes (T1D) do not enter partial clinical remission (PCR); early identification of these patients may improve initial glycemic control and reduce long-term complications. AIM To determine whether routinely obtainable clinical parameters predict non-remission in children and adolescents with new-onset T1D. SUBJECTS AND METHODS Data on remi...
متن کاملCharacteristics and Determinants of Partial Remission in Children with Type 1 Diabetes Using the Insulin-Dose-Adjusted A1C Definition
To evaluate the characteristics and determinants of partial remission (PR) in Belgian children with type 1 diabetes (T1D), we analyzed records of 242 children from our center. Clinical and biological features were collected at diagnosis and during follow-up. PR was defined using the insulin-dose-adjusted A1C definition. PR occurred in 56.2% of patients and lasted 9.2 months (0.5 to 56.6). 25.6%...
متن کاملNew Definition for the Partial Remission Period in Children and Adolescents With Type 1 Diabetes
OBJECTIVE To find a simple definition of partial remission in type 1 diabetes that reflects both residual beta-cell function and efficacy of insulin treatment. RESEARCH DESIGN AND METHODS A total of 275 patients aged <16 years were followed from onset of type 1 diabetes. After 1, 6, and 12 months, stimulated C-peptide during a challenge was used as a measure of residual beta-cell function. RESU...
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متن کاملAltered Suppressor Function of Regulatory T Cells in Type 1 Diabetes
Background: Type 1 diabetes (T1D) is a T cell mediated autoimmune disease targeting the insulin-producing β cells within pancreatic islets. Autoimmune diseases may develop as a consequence of altered balance between regulatory (Tregs) and autoreactive T cells. Objectives: To evaluate Treg cells frequency and suppressive function in the peripheral blood of newly diagnosed T1D patients in compari...
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تاریخ انتشار 2009